The school said on Monday that the mandate clearly violates religious freedom by requiring many religiously affiliated hospitals, schools and charities to comply with the coverage standards.
President Barack Obama offered to soften the mandate to accommodate religious groups, but U.S. Roman Catholic bishops say the change doesn’t go far enough.
Other religious colleges are already suing the Health and Human Service agency and administration officials over the mandate.
The university is the most prominent Roman Catholic school in the country. Notre Dame came under then unprecedented criticism from U.S. bishops and others in 2009 for inviting Obama as commencement speaker. Obama supports abortion rights.